Over 1 Million People Have Been Treated with New Hepatitis Drugs, But Cost...
More than 1 million people have now received hepatitis C treatment using the new highly effective and well-tolerated direct-acting antiviral agents despite their high cost, according to a report...
View ArticleHIV Glasgow: Generic Hepatitis C Drugs Purchased Online Produce High Cure Rates
Use of generic versions of direct-acting antivirals for hepatitis C resulted in very high cure rates for people who obtained the products through 3 buyers’ clubs, indicating that the generic products...
View ArticleCoverage of IDWeek 2016
HIVandHepatitis.com coverage of IDWeek 2016, held October 26-30 in New Orleans. Conference highlights include experimental HIV therapies, PrEP and other biomedical HIV prevention, antibiotic...
View ArticleIDWeek 2016: New Triple DAA Combo Cures 96%-99% of People with Genotype 1-6...
A new 3-drug regimen of sofosbuvir, ledipasvir, and voxilaprevir, taken without ribavirin for 8 weeks, produced sustained virological response in 96% of previously untreated patients with all...
View ArticleAASLD 2016: Liver Cancer Risk Reduced After Hepatitis C Treatment, But...
People who are cured of hepatitis C after a course of direct-acting antiviral treatment do not have a higher risk of developing hepatocellular carcinoma (HCC) -- and probably have a reduced risk --...
View ArticleAASLD 2016: Real-World Responses to HCV Treatment Among U.S. Veterans Match...
Direct-acting antiviral treatment is curing people of hepatitis C in real-world clinical practice at similar rates to those seen in clinical trials, and there do not seem to be major differences...
View ArticleAASLD 2016: Grazoprevir/ Elbasvir + Sofosbuvir Highly Effective for...
A triple regimen of grazoprevir/elbasvir (Zepatier) plus sofosbuvir (Sovaldi) without ribavirin cured 96% of previously untreated and 97% of treatment-experienced people with hepatitis C virus (HCV)...
View ArticleAASLD 2016: AbbVie Pangenotypic Combination Cures Hard-to-Treat People with...
AbbVie’s pangenotypic combination of glecaprevir and pibrentasvir cured almost all of the hardest-to-treat genotype 3 hepatitis C patients -- those with cirrhosis or previous treatment experience --...
View ArticleAASLD 2016: AbbVie Pangenotypic Combination Cures 98% or More Across HCV...
AbbVie’s combination of glecaprevir and pibrentasvir cured at least 98% of people with hepatitis C in 3 large clinical trials covering 5 out of 6 genotypes of the virus, and it is likely to receive...
View ArticleAASLD 2016: 8-Week Triple Combo Cures Most Patients with Genotype 1-6...
A 3-drug regimen of sofosbuvir, velpatasvir, and voxilaprevir taken for 8 weeks demonstrated an overall sustained virological response rate of 95% for previously untreated patients with all hepatitis...
View ArticleAASLD 2016: U.S. Veterans Health System and Australia Show Potential for...
If sufficient money is available to pay for direct-acting antivirals (DAAs), the U.S. Veterans Health Administration could cure hepatitis C in the majority of veterans under its care within 3 years,...
View ArticleCoverage of the 2016 AASLD Liver Meeting
HIVandHepatitis.com coverage of the 2016 American Association for the Study of Liver Diseases (AASLD) Liver Meeting in Boston, November 11-15, 2016. Conference highlights include direct-acting...
View ArticleAASLD 2016: Grazoprevir Triple Regimen Demonstrates High Cure Rates, Even for...
A new 3-drug coformulation containing Merck's grazoprevir plus the investigational agents MK-3682 and ruzasvir was highly effective for people with hepatitis C virus (HCV) genotypes 1, 2, or 3, with...
View ArticleAASLD 2016: Primary Care Providers Can Effectively Treat Patients with...
Primary care providers such as non-specialist physicians and nurse practitioners can be quickly trained to provide direct-acting antiviral (DAA) therapy for hepatitis C with a high level of treatment...
View ArticleAASLD 2016: Hepatitis C Virus Infection Rising Among Gay Men in San Diego
The prevalence of hepatitis C virus (HCV) infection among HIV-positive men who have sex with men in San Diego has increased over the past 15 years, especially among men who do not inject drugs but use...
View ArticleAASLD 2016: Non-Adherence Is Most Important Risk Factor for...
Research carried out by researchers at Mount Sinai Medical Center in New York found that non-adherence was the strongest risk factor for treatment failure in people taking sofosbuvir/ledipasvir...
View ArticleAASLD 2016: 6 Weeks of Sofosbuvir/Ledipasvir Cures Genotype 1 Acute Hepatitis C
A short course of sofosbuvir/ledipasvir (Harvoni) taken for 6 weeks cured 100% of HIV-negative people with genotype 1 acute hepatitis C virus (HCV) infection, including those with high viral loads,...
View ArticleAASLD 2016: AbbVie Pangenotypic Combination Cures Hard-to-Treat People with...
AbbVie’s pangenotypic combination of glecaprevir and pibrentasvir cured almost all of the hardest-to-treat genotype 3 hepatitis C patients -- those with cirrhosis or previous treatment experience --...
View ArticleAASLD 2016: Curing Hepatitis C May Help Reduce Kidney Disease Progression
People who achieved sustained virological response to interferon-based hepatitis C treatment experienced significantly less decline in kidney function, especially if they had liver cirrhosis,...
View ArticleAASLD 2016: Glecaprevir/ Pibrentasvir Effective for Hepatitis C Patients with...
A 2-drug pangenotypic regimen combining AbbVie's glecaprevir and pibrentasvir demonstrated a high sustained response rate for chronic hepatitis C patients with severe kidney impairment, according to...
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